Inhibitors of human plasmin derived from the Kunitz domains

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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435 692, 4352523, 4353201, 536 235, 530300, 530324, C12P 2106, C12N 1509, C12N 120, C12N 1500, C07H 2104

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active

060717238

ABSTRACT:
This invention provides oligonucleotides encoding novel Kunitz domain polypeptides capable of binding plasmin, and vectors and transformed host cells containing these polynucleotides.

REFERENCES:
patent: 4118481 (1978-10-01), Schanbel et al.
patent: 4153687 (1979-05-01), Schnabel et al.
patent: 5223409 (1993-06-01), Ladner et al.
Adelman et al., Blood, 68(6):1280-1284 (1986).
Anba et al., Biochimie, 70(6):727-733 (1988).
Auerswald et al., Bio. Chem. Hoppe-Seyler, 369(Suppl):27-35 (1988).
Baneyx & Georgiou, J. Bacteriol., 173(8):2696-2703 (1991).
Baneyx and Georgiou, J. Bacteriol., 172(1):491-484 (1990).
Browne et al., GeneBank, Accession No. M74220 (1991).
Broze et al., Biochemistry, 29(33):7539-7546 (1990).
Colman et al., Hemostasis and Thrombosis, Second Edition (Colman et al., eds; ISBN 0-397-50679-1) Chap. 1, pp 3-17 (1987).
Dennis and Lazarus, J. Biol. Chem., 269(35):22129-22136 (1994).
Dennis and Lazarus, J. Biol. Chem., 269(35):22137-22144 (1994).
Eigenbrot et al., Protein Engineering, 3(7):591-598 (1990).
Ellis et al., Ann. NY Acad. Sci., 667:13-31 (1992).
Fidler and Ellis, Cell, 79:185-188 (1994).
Fraedfich et al., Thorac. Cardiovasc. Surg., 37(2):89-91 (1989).
Gardell, Toxicol. Pathol., 21(2):190-198 (1993).
Girard et al., J. Biol. Chem., 266(8):5036-5041 (1991).
Girard et al., Nature, 338:518-20 (1989).
Greg et al., Bio/Technology, 11:905-910 (1993).
Hoover et al., Biochemistry, 32:10936-10943 (1993).
Hynes et al., Biochemistry, 29:10018-10022 (1990).
Kido et al., Biochem. Biophys. Res. Comm., 167(2):716-721 (1990).
Kido et al., J. Biol. Chem., 263(34):18104-18107 (1988).
Kurjan and Herkowwitz, Cell, 30:933-943 (1982).
Laskowski and Kato, Ann. Rev. Biochem., 49:593-626 (1980).
Leatherbarrow and Salacinski, Biochemistry, 30(44):1071710721 (1991).
Lohmann and Marshall, Refract. Corneal. Surg. 9(4):300-302 (1993).
Lucas et al., J. Biol. Chem., 258(7):4249-4256 (1983).
Mann and Lundblad, Hemostasis and Thrombosis, Second Edition (Colman et al., eds; ISBN 0-397-50679-1) Chapt. 10, pp148-161 (1987).
Miyajima et al., Gene, 37:155-161 (1985).
Neuhaus et al., Lancet, 2(8668)924-925 (1989).
Novotny et al, J. Biol. Chem., 264(31):18832-18837 (1989).
O'Reilly et al., Cell, 79:315-328 (1994).
Park and Tulinsky, Biochemistry, 25(14):3977-3982 (1986).
Putterman, Acta Chir. Scand., 155(6-7:)367 (1989).
Robbins, Hemostasis and Thrombosis, Second Edition (Colman et al., eds; ISBN 0-397-50679-1), Chap. 21, pp340-357 (1987).
Schechter and Berger, Biochem. Biophys. Res. Commun. 32(5):898-902 (1968).
Schechter and Berger, Biochem. Biophys. Res. Commun., 27(2):157-162 (1967).
Schnabel et al., Biol. Chem. Hoppe-Seyler, 367:1167-1176 (1986).
Sheridan et al., Dis. Colon Rectum, 32(6):505-508 (1989).
Sprecher et al., PNAS USA, 91:3353-3357 (1994).
Van Dijl et al., EMBO J., 11(8):2819-2828 (1992).
Varadi and Patthy, Biochemistry, 23(9):2108-2112 (1984).
Varadi and Patthy, Biochemistry, 22(10):2440-2446 (1953).
Vedvick et al., J. Ind. Microbiol., 7:197-201 (1991).
Wagner et al., Biochem. Biophys. Res. Comm., 186:1138-1145 (1992).
Wun et al., J. Biol. Chem. 263(13):6001-6004 (1988).

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