Inhibitors of HIV protease

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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546169, 544355, 549 58, 549 77, 549493, 560 13, 560 17, 564 48, 564 56, 564153, C07D21548, C07D21726

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active

054342651

ABSTRACT:
The present invention provides novel HIV protease inhibitors, pharmaceutical formulations containing those compounds and methods of treating HIV infection.

REFERENCES:
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Blumenstein et al., Biochemical and Biophysical Research Comm., vol. 163 (2), pp. 980-987 (1989).
Meek et al., Proc. Nat. Acad. Sci., USA, vol. 86, pp. 1841-1845 (1989).
Roberts, N. A. et al., Science, 248, 358-361 (1990).
Vara Prasad, J. V. N. et al., Peptides, Chemistry and Biology, Proceeding of the Twelfth American Peptide Symposium, Jun. 16-21, 721-722 (1991).
Thaisrivongs, S. et al., J. Med Chem, 34, 2344-2356 (1991).

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