Inhibitors of HCV replication

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C514S233200, C514S254080, C514S323000, C514S339000, C514S364000, C514S365000, C514S394000, C514S397000, C514S410000, C514S414000, C514S422000, C540S576000, C544S142000, C544S372000, C546S200000, C546S276700, C548S131000, C548S132000, C548S181000, C548S305100, C548S312100, C548S420000, C548S455000, C548S518000

Reexamination Certificate

active

07153848

ABSTRACT:
Indole compounds of Formula I are described. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV. Different forms and compositions comprising the compounds are also described as well as methods of preparing the compounds.

REFERENCES:
patent: 2005/0119318 (2005-06-01), Hudyma et al.
patent: WO 01/47883 (2001-07-01), None
patent: WO 02/04425 (2002-01-01), None
patent: WO 03/007945 (2003-01-01), None
patent: WO 03/010140 (2003-02-01), None
patent: WO 03/010141 (2003-02-01), None
patent: WO 2004/064925 (2004-08-01), None
patent: WO 2004/065367 (2004-08-01), None
patent: WO 2004/087714 (2004-10-01), None
patent: WO 2004/099241 (2004-11-01), None
patent: WO 2005/012288 (2005-02-01), None
patent: WO 2005/014543 (2005-02-01), None
patent: WO 2005/034941 (2005-04-01), None
patent: WO 2005/080388 (2005-09-01), None
patent: WO 2005/080399 (2005-09-01), None
Rivara et al. “Three-Dimensional Quantitative Structure-Activity Relationship Studies on Selected MT1 and MT2 Melatonin Receptor Ligands: Requirements for Subtype Selectivity and Intrinsic Activity Modulation” J. Med. Chem. 2003, vol. 46, pp. 1429-1439.
S. Harper, et al, “Potent Inhibitors of Subgenomic Hepatitis C Virus RNA Replication Through Optimization of Indole-N-Acetamide Allosteric Inhibitors of the Viral NS5B Polymerase,” J. Med. Chem., 48(14), pp. 4547-4557, 2005.
S. Harper, et al, “Development and Preliminary Optimization of Indole-N-Acetamide Inhibitors of Hepatitis C Virus NS5B Polymerase,” J. Med. Chem., 48(5), pp. 1314-1317, 2005.
Grinev, A.N., et al, “Synthesis and Biological Activity of Aminoacetyl and Aminoethyl Derivatives of Indole [1,2-c] Quinazoline,” Khimiko-Farmatsevticheskii Zhurnal, Vses. Nauchno-Issled. Khim-Farm. Inst., 12(2), pp. 97-101, 1978-Coden: Khfzan; ISSN: 0023-1134 (English Abstract).

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