Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2006-05-30
2006-05-30
Owens, Amelia A. (Department: 1625)
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C546S280400
Reexamination Certificate
active
07053223
ABSTRACT:
The present invention discloses the identification of the novel inhibitors of farnesyl protein transferase and ras protein farnesylation. The compounds and pharmaceutical compositions disclosed herein are useful in treating diseases associated with farnesyl protein transferase, such as cancer.
REFERENCES:
patent: 5639778 (1997-06-01), Andersson et al.
Crul et al Phase I Clinical and Pharmacologic Study of Chronic Oral Administration of ht Parnesyl Protein Transferase Inhibitor R115777 in Advanced Cancer J. clinical Oncology, 20(11), Jun. 1, 2002, 2726-2735.
Bristol--Myers Squibb Company
Gibbons Maureen S.
Owens Amelia A.
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