Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1998-10-13
2000-08-15
Raymond, Richard L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514250, 540456, 540468, 544349, A61K 31504, A61K 31553, C07D48708, C07D49808
Patent
active
061037230
ABSTRACT:
The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras.
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Bergman Jeffrey M.
Dinsmore Christopher J.
Graham Samuel L.
Daniels Mark R.
Merck & Co. , Inc.
Pecoraro Dianne
Raymond Richard L.
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