Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1997-03-26
1998-07-14
Davis, Zinna Northington
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514399, 546333, 546338, 5483751, C07D23354, C07D21302, A61K 3144, A61K 31415
Patent
active
057804885
ABSTRACT:
The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras.
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Bergman Jeffrey
Dinsmore Christopher
Billups Richard C.
Daniel Mark R.
Davis Zinna Northington
Merck & Co. , Inc.
Pecoraro Dianne
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