Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1997-09-05
1998-08-04
Fan, Jane
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
549382, 549297, 549384, A61K 31365, C07D49306
Patent
active
057894388
ABSTRACT:
The present invention is directed to steroidal or terpenoidal compounds which inhibit farnesyl-protein transferase (FPTase). The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and treatment of cancer.
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Lingham Russell B.
Martin Isabel
Pelaez Fernando
Sanchez Manuel
Silverman Keith C.
Daniel Mark R.
Fan Jane
Korsen Elliott
Merck & Co. , Inc.
Muthard David A.
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