Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1998-06-18
1999-12-07
Richter, Johann
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514326, 514365, 514367, 514400, 514406, 544295, 5462727, 546190, 548180, 548200, 5483381, 5483741, A01N 4354, C07D40312, C07D21132, C07D27764
Patent
active
059984244
ABSTRACT:
The present application describes inhibitors of factor Xa with a neutral P1 specificity group of formula I: ##STR1## or pharmaceutically acceptable salt forms thereof, wherein R and E may be groups such as methoxy and halo.
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Jaszberenyi et al., Enzyme Inhibitor Interactions, Sejtosztodas Farmakol. 10(1) pp. 75-92 (see abstract), Dec. 1992.
Dominguez Celia
Fevig John M.
Galemmo, Jr. Robert A.
Han Qi
Lam Patrick Y.
DuPont Pharmaceuticals Company
Keating Dominic
Richter Johann
Vance David H.
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