Inhibitors of cyclin dependent kinases as anti-cancer agent

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C544S331000, C548S537000

Reexamination Certificate

active

10671747

ABSTRACT:
The present invention relates to 2-substituted 4-heteroaryl-pyrimidines, their preparation, pharmaceutical compositions containing them and their use as inhibitors of cyclin-dependent kinases (CDKs) and hence their use in the treatment of proliferative disorders such as cancer, leukaemia, psoriasis and the like.

REFERENCES:
patent: 2003/0092714 (2003-05-01), Cao et al.
patent: 2003/0203926 (2003-10-01), Kois et al.
patent: 0 233 461 (1987-08-01), None
patent: 0 588 762 (1992-08-01), None
patent: WO95/09852 (1995-04-01), None
patent: WO97/19065 (1997-05-01), None
patent: WO 00/39101 (2000-07-01), None
patent: WO 02/46171 (2002-06-01), None
Torley et al., CAPLUS Abstract 18:112478 (RN 112722-32-4), 1988.
Simone, Oncology: Introduction, Cecil Textbook of Medicine, 20thEdition, vol. 1, pp. 1004-1010, 1996.
Blain et al., Differential Interaction of thet Cyclin-dependent Kinase (Cdk) inhibitor p27 with Cyclin-A-Cdk2 and Cyclin D2-Cdk4, The Journal of Biological Chemistry, vol. 272, No. 41, pp. 25863-25872, 1997.
LuValle et al., Cell Cycle Control in Growth Plate Chondrocytes, Frontiers in Bioscience 5, d493-503, May 2000.

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