Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – N-c doai
Patent
1994-02-14
1998-06-09
Reamer, James H.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
N-c doai
514491, 514492, 424650, A61K 3128
Patent
active
057634807
ABSTRACT:
The present invention provides a method for blocking a cellular proton pump that comprises contacting a cell with a cellular proton pump-blocking effective quantity of In-EDTA or Tl-EDTA. The present invention also provides a method of treating or preventing cell-mediated disorders in a vertebrate animal by administering In-EDTA or Tl-EDTA to the vertebrate animal, as well as a method for stopping the cellular proton pump-blocking effect of Group IIIa metals such as Ga, In, and Tl, through use of suitable chelating agents. Suitable compositions for use in the aforementioned methods are provided as well.
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Blair Harry C.
Schlesinger Paul H.
Teitelbaum Steven L.
Reamer James H.
The Jewish Hospital of St. Louis
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