Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2007-12-11
2007-12-11
Anderson, Rebecca (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S410000, C514S367000, C548S233000, C548S219000, C548S235000, C548S455000, C548S159000, C548S218000
Reexamination Certificate
active
11620608
ABSTRACT:
The present invention provides compounds, compositions and methods for the selective inhibition of cathepsin S. In a preferred aspect, cathepsin S is selectively inhibited in the presence of at least one other cathepsin isozyme. The present invention also provides methods for treating a disease state in a subject by selectively inhibiting cathepsin S.
REFERENCES:
Petanceska et al. Journal of Biological Chemistry, 1996, vol. 271, p. 4403-4409.
Saegusa et al. and The journal of Clinical Investigation, 2002, vol. 110, p. 361-369.
Alper Phillip
Chatterjee Arnab
Epple Robert
Liu Hong
Roberts Michael
Anderson Rebecca
Chu Yong
Genomics Institute of the Novartis Research Foundation
IRM LLC
Tongco Wu Emily
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