Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2008-01-01
2008-01-01
Habte, Kahsay (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C544S124000, C544S135000, C544S137000, C544S162000, C544S165000, C514S235800, C514S237800
Reexamination Certificate
active
07314872
ABSTRACT:
The present invention provides compounds, compositions and methods for the selective inhibition of cathepsin S. In a preferred aspect, cathepsin S is selectively inhibited in the presence of at least one other cathepsin isozyme. The present invention also provides methods for treating a disease state in a subject by selectively inhibiting cathepsin S. More particularly, the present invention provides compounds having Formula I:wherein Q is morpholinyl; andA, R5, R6, R7, R8, R9and Ar are substituents.
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Alper Phillip
Bursulaya Badry
Chatterjee Arnab
Guo Jianhua
He Yun
Genomics Institute of the Novartis Research Foundation
Habte Kahsay
IRM LLC
Tongco Wu Emily
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