Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1995-03-02
1998-09-29
Rotman, Alan L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
548140, A61K 31415, A61K 31425, C07D285135
Patent
active
058146466
ABSTRACT:
A method of protecting a warm-blooded mammal from the progression of Alzheimer's disease, which comprises administering an effective amount of a compound of general formula. ##STR1## in which: R.sup.1 represents an optionally substituted aromatic or heteroaromatic group;
REFERENCES:
patent: 3990879 (1976-11-01), Soper
patent: 4021225 (1977-05-01), Hedrich
patent: 4174398 (1979-11-01), Regel
patent: 4175081 (1979-11-01), Driscoll
patent: 4518414 (1985-05-01), Schirmer
patent: 4576629 (1986-03-01), Morland
patent: 4599424 (1986-07-01), Driscoll
patent: 4639526 (1987-01-01), Metzger
patent: 4686294 (1987-08-01), Hoegerle
patent: 4835168 (1989-05-01), Paget
patent: 4876044 (1989-10-01), Cebalo
patent: 4987233 (1991-01-01), Achgill
patent: 5087284 (1992-02-01), Driscoll
U.S. application No. 08/397466 Reel et al. Mar. 02, 1995.
LeBlanc, Metabolic Brain Disease, vol 9(1), pp 3-31, 1994.
Yankner, Science, vol 250, pp279-281, 12 Oct. 1990.
Selkoe, Neuron, vol 6, pp 487-498, Apr. 1991.
Schenk, Jourmal of Medicinal Chemistry, vol 38(21), pp414-4154, 13 Oct. 1995.
Heinz Lawrence J.
Panetta Jill A.
Phillips Michael L.
Reel Jon K.
Shadle John K.
Boone David E.
Eli Lilly and Company
M. Mach D. Margaret
Palmberg Arleen
Rotman Alan L.
LandOfFree
Inhibitors of amyloid beta-protein production does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Inhibitors of amyloid beta-protein production, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Inhibitors of amyloid beta-protein production will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-686635