Inhibitors of aminoglycoside nephrotoxicity

Drug – bio-affecting and body treating compositions – Solid synthetic organic polymer as designated organic active... – Polymer from ethylenic monomers only

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514789, 514 42, 514974, 514 40, 536 134, 536 136, 536 137, 536 14, 536 168, A61K 3171

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active

050792342

ABSTRACT:
Certain water-soluble polyanionic organic acid polymers in the weight range of from about 1,000 to 30,000 daltons may be use to inhibit aminoglycoside nephrotoxicity. These polyanionic polymers are homopolymers or copolymers comprised of monomers selected from acrylic, methacryclic, vinylsulfonic and maleic acids; and are in a pharmaceutically acceptable salt form.

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