Inhibitors of Akt activity

Details Inhibitors of Akt activity Inhibitors of Akt activity

2011-08-23

2011-08-23

Wilson, James O (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C514S252030, C514S269000, C514S256000, C514S236500, C544S238000, C544S242000, C544S335000, C544S111000, C544S122000

Reexamination Certificate

active

08003643

ABSTRACT:
The present invention is directed to compounds which contain substituted pyridazines and pyrimidines moieties which inhibit the activity of Akt, a serine/threonine protein kinase. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for treating cancer comprising administration of the compounds of the invention.

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