Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2007-12-04
2007-12-04
Balasubramanian, Venkataraman (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C544S182000
Reexamination Certificate
active
10554186
ABSTRACT:
The present invention is directed to compounds which contain a heterocyclic triazine moiety which inhibit the activity of Akt, a serine/threonine protein kinase. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for treating cancer comprising administration of the compounds of the invention.
REFERENCES:
patent: 6060491 (2000-05-01), Pruitt et al.
patent: 6159974 (2000-12-01), Ueno et al.
patent: 6960584 (2005-11-01), Carling et al.
patent: 2002/0127214 (2002-09-01), Hemmings
patent: 2004/0102360 (2004-05-01), Barnett et al.
patent: 2004/0106540 (2004-06-01), Barnett et al.
patent: 2004/0116433 (2004-06-01), Owens et al.
patent: 2004/0122012 (2004-06-01), Owens et al.
patent: 2005/0130977 (2005-06-01), Lindsley et al.
patent: 2005/0159422 (2005-07-01), Lindsley et al.
patent: 2005/0182256 (2005-08-01), Duggan et al.
patent: 2005/0222155 (2005-10-01), Bilodeau et al.
patent: 2005/0288294 (2005-12-01), Duggan et al.
patent: WO 97/22360 (1997-06-01), None
patent: WO 01/91754 (2001-12-01), None
patent: WO 02/083138 (2002-10-01), None
patent: WO 03/084473 (2003-10-01), None
Cecil Textbook of Medicine, edited by Bennet, J.C., and Plum F., 20th edition, vol. 1, 1004-1010, 1996.
Hanada et al., Biochimica et Biophysica Acta 1697, 3-16, 2004.
Bellacosa et al., Int. J. Cancer (Pred. Oncol.) 64, 280-285, 1995.
Bilodeau Mark T.
Lindsley Craig W.
Zhao Zhijian
Balasubramanian Venkataraman
Leff Matthew A.
Merck & Co. , Inc.
Muthard David A.
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