Inhibitors of 11-β-hydroxy steroid dehydrogenase type 1

Details Inhibitors of 11-β-hydroxy steroid dehydrogenase type 1 Inhibitors of 11-β-hydroxy steroid dehydrogenase type 1

2007-08-07

2007-08-07

Saeed, Kamal A. (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C548S182000

Reexamination Certificate

active

11135662

ABSTRACT:
The present invention relates to compounds with the formula (I), (II), (III) or (IV):wherein R1, R2, R3, R4, R5, R6, R7, X and Z are as defined herein, and also to pharmaceutical compositions comprising the compounds, as well as methods of use of the compounds for treatment of disorders associated with human 11-β-hydroxysteroid dehydrogenase type 1 enzyme and for the preparation of a medicament which acts on the human 11-β-hydroxysteroid dehydrogenase type 1 enzyme.

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