Inhibitors for replication of retroviruses and for the expressio

Details Inhibitors for replication of retroviruses and for the expressio Inhibitors for replication of retroviruses and for the expressio

1992-11-16

1993-11-23

Rollins, John W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

536 241, 536 245, 514934, A61K 3170, C07H 1700

Patent

active

052644235

ABSTRACT:
Phosphorothioate oligodeoxyribonucleotide analogs can be used to prevent replication of foreign nucleic acids in the presence of normal living cells, as well as to inhibit the proliferation of neoplastic cells.

REFERENCES:
patent: 3687808 (1972-08-01), Merigan, Jr. et al.
patent: 4469863 (1984-09-01), Ts'o et al.
patent: 4511713 (1985-04-01), Miller et al.
J. Amer. Chem Soc. 106: 6077, 1984.
J. Biochem. Biophys. Methods 13:97-102, 1986.
Biochem. Biophys. Res. Comm. 140(2): 735-742 1986.
Cancer Reserach 45(9): 4677s-4684s, 1985.

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