Inhibitors for glycosaminosyl transferase V

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving transferase

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536 41, 536 53, 435193, 436 64, 436501, 436578, 436813, 514 25, C12Q 148, C12N 910, C07H 1502, A61K 3170

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active

050325051

ABSTRACT:
Synthetic glycosaminosyl transferase-V acceptors and inhibitors are disclosed. Minimal trisaccharide inhibitors and acceptors specific for GnT-V, which is associated with the ability of cells to metastasize are useful, in diagnosis and treatment of conditions characterized by metastatic cells.

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