Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving transferase
Patent
1988-11-21
1991-07-16
Griffin, Ronald W.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving transferase
536 41, 536 53, 435193, 436 64, 436501, 436578, 436813, 514 25, C12Q 148, C12N 910, C07H 1502, A61K 3170
Patent
active
050325051
ABSTRACT:
Synthetic glycosaminosyl transferase-V acceptors and inhibitors are disclosed. Minimal trisaccharide inhibitors and acceptors specific for GnT-V, which is associated with the ability of cells to metastasize are useful, in diagnosis and treatment of conditions characterized by metastatic cells.
REFERENCES:
patent: 4770994 (1988-09-01), Rittenhouse
Ahrens et al., J. Biol. Chem. (1987), 262:7575.
Camarasa et al., J. Med. Chem. (1985) 28:40.
Cummings et al., J. Biol. Chem. (1982), 257:11230.
Dennis, Cancer Res. (1986) 46:5131.
Dennis, Cancer Surveys (1988).
Dennis et al., Science (1987) 236:582.
Humphries et al., Science (1986) 233:467.
Irimura et al., Cancer Res. (1981) 41:3411.
Kijima-Suda et al., Cancer Res. (1986) 46:858.
Pierce et al., J. Bio. Chem. (1986) 261:10772.
Schacter, Biochem. Cell. Bio. (1986) 64:163.
Vaghefi et al., J. Med. Chem. (1987) 30:1391.
Yamashida et al., J. Bio. Chem. (1984) 259:10834.
Yamashida et al., J. Bio. Chem. (1985) 260:3963.
Srivastava et al., Carbohydrate Res. (1988) 179:137-161.
Palcic et al.; Glycoconjugate Journal 5:49-63 (1988).
Khare et al.; Carbohydrate Research 136:285-308 (1985).
Shah et al.; Carbohydrate Research 153: 155-161 (1986).
Tahir et al.; Canadian Journal of Chemistry 64:1771-1780 (1986).
Pierce et al.; Biochemical and Biophysical Research Communications 146(2): 679-684 (7/31/87).
Hindsgaul et al.; Carbohydrate Research 173: 263-272 (3/1/88).
Hindsgaul Ole
Pierce James M.
Carson Nancy S.
Chembiomed Ltd.
Griffin Ronald W.
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