Inhibitors against galectins

Details Inhibitors against galectins Inhibitors against galectins

2007-06-12

2007-06-12

Jiang, Shaojia Anna (Department: 1623)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C514S053000, C536S123100

Reexamination Certificate

active

10466933

ABSTRACT:
The present invention relates to novel compounds, the use of said compounds as a medicament as well as for the manufacture of a medicament for treatment of disorders relating to the binding of galectin to receptors in a mammal. Said galectin is preferably a galectin 3.

REFERENCES:
patent: 0 561 523 (1993-09-01), None
patent: WO 00/07624 (2000-02-01), None
patent: WO00/07624 (2000-02-01), None
patent: WO 00/29418 (2000-05-01), None
Lu et al. “Synthesis of a divalent glycoside of an alpha-galactosyl disaccharide epitope involved in the hyperacute rejection of xenotransplantation” (2001) Carbohydrate Research, vol. 334, pp. 289-294.
Stults et al., “Characterization of the substrate specificity of alpha-1,3-galactosyltransferase utilizing modified N-acetyllactosamine disaccharides.” (1999) Glycobiology, vol. 9, No. 7, pp. 661-668.
The Merck Manual of Diagnosis and Therapy, seventeenth edition, 1999, Published by Merck Research Laboratories, pp. 397-398, 948-949, 1916, and 1979-1981.
The Oxford Textbook of Oncology, 1995, published by Oxford University Press, pp. 447-453.
Bresalier et al., “Metastasis of Human Colon Cancer is Altered by Modifying Expression of the Beta-Galactoside-Binding Protein Galectin 3” Gastroenterology (1998) vol. 115, pp. 287-296.
Kiso, M. et al., “Carboymethylgalactose Derivatives”, Patent Abstracts of WIPO No. WO 00/17216, (Mar. 30, 2000).
Helland, A. C. et al., “Methyl 3-Amino-3-Deoxy-.Beta.-D-Galactopyranosyl-(1.fwdarw.4)-2-Acetamido-2-Deoxy-.D-Glucopyranoside:an Inhibitor of UDP-D-Galactose: .Beta.-D-Galactopyranosyl-(1.fwdarw.4)-2-Acetamido-2-Deoxy-D-Glucose (1.fwdarw.3)-.Alpha.-D-Galactopyranosyltransferase”, CAPLUS Abstract of Carbohydr. Res., vol. 276, No. 1, pp. 91-98, (1995).
Bresalier, R. S. et al., “Metastasis of Human Colon Cancer is Altered by Modifying Expression of the .Beta.-Galactoside-Binding Protein Galectin 3”, CAPLUS Abstract of Gastroenterology, vol. 115, No. 2, pp. 287-296, (1998).

Affiliated with

Also associated with

Rating

Inhibitors against galectins does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Inhibitors against galectins, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Inhibitors against galectins will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3852891