Inhibitor protein of the wnt signal pathway

Details Inhibitor protein of the wnt signal pathway Inhibitor protein of the wnt signal pathway

2005-01-18

2005-01-18

Andres, Janet (Department: 1646)

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

C435S069100, C435S320100, C435S325000, C514S002600

Reexamination Certificate

active

06844422

ABSTRACT:
The present invention relates to an inhibitor protein of the wnt signal path, a DNA encoding such a protein and a process for the preparation of such a protein. In addition, this invention concerns the use of the DNA and the protein as well as antibodies directed against the protein.

REFERENCES:
Kaichiro Sawada, Kiyokazu Agata and Goro Eguchi; “Characterization of Terminally Differentiated Cell State by Categorizing cDNA Clones Derived From Chicken Lens Fibers”; Int. J. Dev. Biol. 40:531-535 (1996).
Andrei Glinka, Wei Wu, Darya Onichtchouk, Claudia Blumenstock and Christof Niehrs; “Head Induction By Simultaneous Repression of Bmp and Wnt Signaling In Zenopus”; Nature 389:517-519 (1997).
Andrei Glinka, Wei Wu, Hajo Delius, A. Paula Monaghan, Claudia Blumenstock and Christof Niehrs; “Dickkopf-1 Is a Member Of a New Family of Secreted Proteins and Functions in Head Induction”, Nature 391:357-362 (1998).
EMVRT Database, Accession No. D26311, Jul. 29, 1994.

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