Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1995-06-01
1997-02-18
Henley, III, Raymond
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
A61K 3170
Patent
active
056042108
ABSTRACT:
The present invention relates to prevention or treatment a brain edema, an intracranial hemorrhage and a cerebral infarction by administering a pharmaceutically effective amount of a compound or a pharmaceutically acceptable salt thereof, for inhibiting a vascular permeability enhancer, which the compound is of the formula: ##STR1## wherein A is halogen, --X--R.sup.3 in which X is O, S, NH or NHNH, and R.sup.3 is H, acyl, a hydrocarbon group or an aromatic heterocyclic group, or --Y.dbd.R.sup.4 in which Y is N or NHN, and R.sup.4 is a divalent hydrocarbon group, and R.sup.1 is H, halogen, a hydrocarbon group, a heterocyclic group or --Z--R.sup.5 in which Z is O, S or NH, and R.sup.5 is H, a hydrocarbon group or an aromatic heterocyclic group;
REFERENCES:
patent: 3819613 (1974-06-01), Marumoto et al.
patent: 4225591 (1980-09-01), Marumoto et al.
patent: 4255565 (1981-03-01), Marumoto et al.
patent: 4341769 (1982-07-01), Marumoto et al.
Asano Tsuneo
Goto Giichi
Imamoto Tetsuji
Nagaoka Akinobu
Sugiura Yoshihiro
Henley III Raymond
Takeda Chemical Industries Ltd.
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