Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1994-04-08
1995-07-04
Tsang, Cecilia
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
549235, A61K 3134, C07D30777
Patent
active
054300550
ABSTRACT:
The culture ATCC 74256 and its mutants are capable of producing zaragozic acid A and other squalene synthase inhibitors.
The compound of formula I herein may be prepared from culture ATCC 74256 and is useful in the treatment of fungal infections, and inhibition of squalene synthase, and protein farnesyltransferase.
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Dabrah Thomas T.
Harwood, Jr. H. James
Huang Liang H.
Kaneko Takushi
Creagan B. Timothy
Holtrust Gezina
Pfizer Inc.
Richardson Peter C.
Tsang Cecilia
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