Inhibitor of cell proliferation and methods of use thereof

Details Inhibitor of cell proliferation and methods of use thereof Inhibitor of cell proliferation and methods of use thereof

2007-08-14

2007-08-14

Vogel, Nancy (Department: 1636)

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Fungi

C435S254230, C435S320100, C435S325000, C435S419000, C536S023400

Reexamination Certificate

active

10751380

ABSTRACT:
An chimerical polypeptide that arrests proliferating cells in mitosis is provided. In general the polypeptide has an N-terminal transit peptide, such as HIV-1 Tat, and a C-terminal cell-cycle effector, such as a G2/M cyclin or a cytostatic factor. A polynucleotide under the control of a heterologous promoter that encodes a polypeptide that arrests cells in mitosis is also provided. The polynucleotide may, for example, encode a G2/M cyclin. Pharmaceutical compositions comprising the agent that inhibits transit through mitosis is provided. A method of treating patients suffering from a hyperplasia, such as cancer, psoriasis or benign prostate hyperplasia is provided.

Affiliated with

Also associated with

Rating

Inhibitor of cell proliferation and methods of use thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Inhibitor of cell proliferation and methods of use thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Inhibitor of cell proliferation and methods of use thereof will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3866207