Inhibitor for delta 5-desaturase

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Conjugate or complex

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Details

514 80, 514885, A61K 3578, A61K 31675

Patent

active

053364961

ABSTRACT:
A composition for inhibiting .DELTA..sup.5 -desaturase comprising an effective ingredient selected from the group consisting of lignan compounds, curcumin and piperonyl butoxide. As the lignan compounds sesamin, sesaminol, episesamin, episesaminol, sesamolin, 2-(3,4-methylenedioxyphenyl)-6-(3-methoxy-4 -hydroxyphenyl)-3,7-dioxabicyclo[3.3.0]octane, 2,6-bis-(3-methoxy-4-hydroxyphenyl)-3,7-dioxabicyclo[3.3.0]octane, and 2-(3,4-methylenedioxyphenyl)-6 -(3-methoxy-4-hydroxyphenoxy)-3,7-dioxabicyclo[3.3.0]-octane are used. Moreover the effective ingredient may be a sesame oil extract or sesame seed extract.

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Biological Abstract No. 76059455, Mukhopadhyay et al, "Anti Inflammatory and Irritant Activities of Curcumin Analogs in Rats".

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