Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1995-03-28
1998-12-15
Robinson, Douglas W.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C07H 2104
Patent
active
058499008
ABSTRACT:
The present invention provides methods of inhibiting a virus with which a vertebrate is infected and which replicates via an RNA template comprising the administration of an antisense or triplex-forming oligonucleotide or a derivative thereof capable of binding to a polypurine-rich tract in a region of single-stranded RNA or RNA-DNA hybrid, respectively. Chimeric oligonucleotides capable of forming triplex structures with single-stranded nucleic acids are also disclosed.
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Max-Planck-Gesellschaft zur Forderung der Wissenschafter e.V.
Nelson Amy J.
Robinson Douglas W.
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