Inhibition of vascular stenosis

Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Monoclonal antibody or fragment thereof

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Details

4241581, 5303871, 53038824, 5303892, A61K 39395, C07K 1622

Patent

active

056480768

ABSTRACT:
Methods for inhibiting vascular stenosis in a mammal, including restenosis following surgical removal of atherosclerotic plaques. Inhibition is achieved through the administration of anti-growth factor antibodies, including anti-FGF antibodies and anti-PDGF antibodies.

REFERENCES:
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V. Lindner et al., "Proliferation of Smooth Muscle Cells After Vascular Injury is Inhibited by an Antibody Against Basic Fibroblast Growth Factor", Proc. Natl. Acad. Sci. USA 88: 3739-3743, 1991.
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