Inhibition of urinary calculi growth

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...

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514106, 514891, 424601, 424604, A61K 3166

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active

055917305

ABSTRACT:
The present invention provides metal ion/bisphosphonate complexes that are useful for the treatment and diagnosis of urinary calculi. Preferred bisphosphonates include etidronate, pamidronate (APD), methylene diphosphonate (MDP), and imidodiphosphonate (IDP). The metal ion is preferably a quadrivalent metal ion such as Sn.sup.+4.

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