Inhibition of tumor growth by antisense oligonucleotides for IL-

Details Inhibition of tumor growth by antisense oligonucleotides for IL- Inhibition of tumor growth by antisense oligonucleotides for IL-

1998-04-06

2000-01-25

Elliott, George C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

435 6, 435375, 435377, 536 241, 536 245, A61K 4800, C07H 2104

Patent

active

060178981

ABSTRACT:
Oligonucleotides are provided which are effective in inhibiting the growth, metastasis and/or angiogenesis of tumors, including particularly melanoma and/or lung cancer. Methods are also provided for use of these oligonucleotides in the treatment of diseases.

REFERENCES:
Branch "A Good Antisense Molecule is Hard to Find" TIBS vol. 23: 45-50, 1998.
Agrawal "Antisense Oligonucleotides: Towards Clinical Trials." TIBTECH vol. 14: 376-387, 1996.

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