Inhibition of TNF-.alpha. pleiotropic and cytotoxic effects

Details Inhibition of TNF-.alpha. pleiotropic and cytotoxic effects Inhibition of TNF-.alpha. pleiotropic and cytotoxic effects

1996-11-27

1998-11-10

Walsh, Stephen

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 8, 514 16, 514921, 514885, 530322, A61K 3805

Patent

active

058344357

ABSTRACT:
The pleiotropic effects of TNF alfa in a wide variety of mammalian cell types is decreased and treated by administering glucosaminylmuramyl peptides with D-amino acid residue in a second or third position from the proximal end. New methods for nonspecific oral, vaginal, and topic inhibition is proposed. Inhibition of cytotoxicity of TNF alfa is also achieved.

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