Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...
Patent
1980-03-05
1981-06-16
Schwartz, Richard A.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Parasitic organism or component thereof or substance...
424250, 424251, 424263, 424270, 544238, 544322, 544328, 544331, 544405, 546273, 548181, 548252, 548254, 548336, A61K 31415, C07D40306
Patent
active
042737826
ABSTRACT:
Novel 3-(1-Imidazolylalkyl)indoles and the pharmaceutically acceptable acid addition salts thereof are disclosed. The novel compounds are useful in selectively inhibiting the action of the thromboxane synthetase enzyme without significantly inhibiting the action of the prostacycline synthetase or cyclooxygenase enzymes and are thus of value as therapeutic agents for the treatment of ischaemic heart disease, stroke, transient ischaemic attack, thrombosis, migraine and the vascular complications of diabetes.
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Cross Peter E.
Dickinson Roger P.
Knuth Charles J.
Murphy Francis X.
Pfizer Inc.
Richardson Peter C.
Schwartz Richard A.
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