Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2006-06-14
2008-09-30
Angell, Jon E. (Department: 1635)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C536S023100, C514S04400A, C435S004000, C435S006120, C435S375000
Reexamination Certificate
active
07429656
ABSTRACT:
The present invention relates to therapeutic agents useful for the treatment of Severe Acute Respiratory Syndrome (SARS) in humans. In particular, the present invention relates to RNA interference (RNAi) molecules useful for inhibiting the infection and replication of hSARS virus. Preferably, the RNAi molecules target the replicase region of the hSARS virus, or combinations of different sites of hSARS virus genes. The present invention further encompasses methods of using the RNAi molecules for preventing and/or treating SARS. Vaccines and kits comprising therapeutically effective amounts of the RNAi molecules are also encompassed.
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patent: WO-2004/092383 (2004-10-01), None
He et all., JAMA 290:2665-2666, 2003.
Paroo et al (Trends in Biotechnology 22:390-392, 2004).
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Prentice et al (Journal of Virology 78:9977-9986, 2004, not prior art).
Guan Yi
He Ming-Liang
Kung Hsiang-Fu
Lin Marie Chia-Mi
Peng Ying
Angell Jon E.
Saliwanchik Lloyd & Saliwanchik
Shin Dana
The University of Hong Kong
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