Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Reexamination Certificate
2006-10-31
2006-10-31
Mosher, Mary E. (Department: 1648)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
C435S236000, C435S238000, C435S320100, C435S325000, C435S317100, C536S024500, C536S023720, C536S024320, C536S024330
Reexamination Certificate
active
07129223
ABSTRACT:
The present invention relates to therapeutic agents useful for the treatment of Severe Acute Respiratory Syndrome (SARS) in humans. In particular, the present invention relates to RNA interference (RNAi) molecules useful for inhibiting the infection and replication of hSARS virus. Preferably, the RNAi molecules target the replicase region of the hSARS virus, or combinations of different sites of hSARS virus genes. The present invention further encompasses methods of using the RNAi molecules for preventing and/or treating SARS. Vaccines and kits comprising therapeutically effective amounts of the RNAi molecules are also encompassed.
REFERENCES:
patent: 2001/0053519 (2001-12-01), Fodor et al.
patent: WO 2004/092383 (2004-10-01), None
He et al, JAMA 290:2665-2666, 2003.
Paroo et al (Trends in Biotechnology 22:390-392, 2004).
Genbank Accession No. AY274119, “SARS Coronavirus Tor2, complete genome,” version AY274119.1, Apr. 14, 2003.
SARS-associated Coronavirus. Genomic Sequence Availability. [online] [retreived on Aug. 8, 2005]. Retreived from the Internet <URL: http://www.bcgsc.ca/bioinfo/SARS>.
Prentice et al (Journal of Virology 78:9977-9986, 2004, not prior art).
Guan Yi
He Ming-Liang
Kung Hsiang-Fu
Lin Marie Chia-Mi
Peng Ying
Mosher Mary E.
The University of HongKong
LandOfFree
Inhibition of SARS-associated coronavirus (SCoV) infection... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Inhibition of SARS-associated coronavirus (SCoV) infection..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Inhibition of SARS-associated coronavirus (SCoV) infection... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3719393