Inhibition of protein kinase C by long-chain bases

Details Inhibition of protein kinase C by long-chain bases Inhibition of protein kinase C by long-chain bases

1988-05-17

1990-06-26

Griffin, Ronald W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514 28, 536 5, A61K 3170

Patent

active

049372327

ABSTRACT:
Compositions for inhibiting protein kinase C, comprising an inhibitory amount of a compound having the formula: ##STR1## wherein Q is a hydrophobic group; wherein X is --CH.sub.2 --CH.sub.2 -- or --CH.dbd.CH--, which may be substituted by one or more halogens or C.sub.1 -C.sub.3 alkyl groups,

REFERENCES:
patent: 4476119 (1984-10-01), Della Valle et al.
patent: 4544552 (1985-10-01), Fraefel et al.
patent: 4582821 (1986-04-01), Kettner et al.
patent: 4614796 (1986-09-01), Kawamata et al.
patent: 4639437 (1987-01-01), Della Valle et al.
patent: 4673667 (1987-06-01), Catsimpoolas
patent: 4707469 (1987-11-01), Della Valle et al.
patent: 4710490 (1987-12-01), Catsimpoolas et al.

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