Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1984-07-12
1987-03-31
Brown, Johnnie R.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
514 48, 514 49, 536 27, 536 28, 536 29, A61K 3170
Patent
active
046543260
ABSTRACT:
Viral diseases in plant parts, such as leaves are inhibited by applying to the plants an effective amount of an agent comprising 2', 5'-oligonucleotide, such as 2, 5-A, linked in 2', 5'-phosphodiester bond. The agent is provided in a vehicle such as a liquid or a powder, and is present in the vehicle in an effective amount at a concentration less than 1.times.10.sup.-8 M.
REFERENCES:
Devash et al., Multiplication of Tobacco Mosaic Virus in Tobacco Leaf Discs is Inhibited by (2'-5') Oligoadenylate, Chem Abstracts 97:36235x (1982).
Reichman et al., Human Leukocyte Interferon and the Antiviral Factor (AVF) from . . . Plants Stimulate Plant . . . Nucleotides with Antiviral Activity, Chem Abstracts 99:156589d (1983).
Eppstein et al., Analogs of PPP (A2'P)nA. Correlation of Structure . . . with Stability and Biological Activity, Chem Abstracts 98:32781v (1983).
Devash et al., 5'-Dephosphorylated 2',5'-Adenylate Trimer . . . Inhibition of Tobacco Mosaic Virus in . . . Intact Tobacco Plants, Chem Abstracts 100:188949b (1984).
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