Inhibition of phosphoinositide 3-kinase β

Organic compounds -- part of the class 532-570 series – Organic compounds – Four or more ring nitrogens in the bicyclo ring system

Reexamination Certificate

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Reexamination Certificate

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07598377

ABSTRACT:
The present invention relates to selective inhibitors of phosphoinositide (PI) 3-kinase β, use of the selective inhibitors in anti-thrombotic therapy, and a method for screening compounds useful for the new anti-thrombotic therapy by detecting selective inhibitory activity of PI 3-kinase β of the compound. The invention also relates to novel compounds that are inhibitors of PI 3-kinase.

REFERENCES:
patent: 5703075 (1997-12-01), Gammill et al.
patent: 6977255 (2005-12-01), Robertson et al.
patent: 7405211 (2008-07-01), Robertson et al.
patent: WO 0153266 (2001-07-01), None

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