Inhibition of phosphatidylinositol 3-kinase with wortmannin and

Details Inhibition of phosphatidylinositol 3-kinase with wortmannin and Inhibition of phosphatidylinositol 3-kinase with wortmannin and

1993-07-19

1995-01-03

Henley, III, Raymond J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514468, A61K 3135, A61K 3134

Patent

active

053787250

ABSTRACT:
Wortmannin and certain of its analogs are inhibitors of phosphatidylinositol 3-kinase. The compounds are particularly useful for inhibiting phosphatidylinositol 3-kinase in mammals and for treating phosphatidylinositol 3-kinase-dependent conditions, especially neoplasms, in mammals.

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