Inhibition of olfactory neurosensory function to treat...

Details Inhibition of olfactory neurosensory function to treat... Inhibition of olfactory neurosensory function to treat...

2006-09-27

2008-10-14

Haghighatian, Mina (Department: 1616)

Drug, bio-affecting and body treating compositions

Effervescent or pressurized fluid containing

Organic pressurized fluid

C424S046000, C424S434000, C424S489000, C514S909000, C514S866000

Reexamination Certificate

active

07435407

ABSTRACT:
The use of calcium channel blockers administered intra-nasally to inhibit olfactory sensory perception to treat eating disorders, including obesity, is described. Also described is a method of reducing food intake in a subject by administering a pharmaceutical composition comprising an effective amount of a calcium channel blocker to the nasal mucosa, as well as screening methods for drugs to be used in treating obesity or associated disorders.

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patent: 2003/0032595 (2003-02-01), Desir et al.
Watt, W.C. and Storms, D.R., J. Biol. Chem., 2001; 276(1):2047-2052.
Wong et al., Neuron, 2000; 27:487-97.

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