Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...
Patent
1993-05-17
1995-10-10
Kenley, III, Raymond
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Radical -xh acid, or anhydride, acid halide or salt thereof...
514825, 514895, 514903, A61K 3119
Patent
active
054571294
ABSTRACT:
A novel method of inhibiting production of two important mediators of cellular function, tumor necrosis factor and nitric oxide, and treating a pathophysiological state characterized by an undesirable production or level of tumor necrosis factor or nitric acid. The methods of the present invention employ retinoic acid compounds. The most preferred retinoic acid is all-trans-retinoic acid.
REFERENCES:
patent: 5157046 (1992-10-01), Van Wauwe et al.
patent: 5264578 (1993-11-01), Chandraratna
Chemical Abstracts (114: 79814x) 1991.
Aggarwal Bharat B.
Mehta Kapil
Adler Benjamin Aaron
Kenley, III Raymond
Research Development Foundation
Weddington K. E.
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