Inhibition of major groove DNA binding proteins by modified...

Details Inhibition of major groove DNA binding proteins by modified... Inhibition of major groove DNA binding proteins by modified...

2005-10-25

2005-10-25

LeGuyader, John L. (Department: 1635)

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

Method of regulating cell metabolism or physiology

C424S070170, C536S018700

Reexamination Certificate

active

06958240

ABSTRACT:
This invention provides improved polyamides comprising a positive patch for contacting the phosphate backbone or major groove of a DNA molecule. As such, the improved polyamides are capable of inhibiting the function or binding of a DNA-binding protein to a DNA molecule. The improved polyamide provides for more efficient function of the polyamide.

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