Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1987-06-17
1988-12-27
Rollins, John W.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514885, 514908, A61K 3144
Patent
active
047941146
ABSTRACT:
A method of inhibiting the 5-lipoxygenase pathway in an animal in need thereof which comprises administering an effective, 5-lipoxygenase pathway inhibiting amount of a diaryl-substituted imidazole fused to a thiazole pyrrolidine, thiazide or piperidine ring to such animal.
REFERENCES:
patent: 4064260 (1977-12-01), Chefkofsky et al.
patent: 4110460 (1978-08-01), Baetz et al.
patent: 4153706 (1979-05-01), Bender et al.
patent: 4175127 (1979-11-01), Bender et al.
patent: 4186205 (1980-01-01), Bender et al.
patent: 4263311 (1981-04-01), Bender et al.
patent: 4507481 (1985-03-01), Davidson et al.
Lantos et al., J. Med. Chem., 27, 72-75 (1984).
Bender et al., J. Med. Chem., 28, 1169-1177 (1985).
Hagmann et al., Naturwissenschaften, 69, 594 (1982).
Galanos et al., Proc. Natl. Acad. Sci., USA, 76, 5939 (1979).
Bender Paul E.
Griswold Don E.
Hanna Nabil
Lee John C.
Canter Carol G.
Lentz Edward T.
Lourie Alan D.
Rollins John W.
SmithKline Beckman Corporation
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