Inhibition of HTLV-III by exogenous oligonucleotides

Details Inhibition of HTLV-III by exogenous oligonucleotides Inhibition of HTLV-III by exogenous oligonucleotides

1986-05-23

1989-02-21

Nucker, Christine M.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving virus or bacteriophage

424 89, 435 6, 435 29, 435 32, 514 44, 536 26, 536 27, 536 28, C12Q 170, C12Q 102, A61K 3912

Patent

active

048064637

ABSTRACT:
Inhibition of HTLV-III by adminstration of an oligonucleotide complementary to highly conserved regions of the HTLV-III genome necessary for HTLV-III replication and/or gene expression is described, as are oligodeoxynucleotide sequences which are complementary to those regions, methods of inhibiting HTLV-III replication and gene expression and methods of determining the presence or absence of HTLV-III virus in samples such as blood, saliva, urine and tears.

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