Inhibition of HIV and other retroviruses by polyoxoanions

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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Details

514185, 514 2, A61K 31555, A01N 5502, C22C 1400

Patent

active

050933272

ABSTRACT:
There are disclosed pharmaceutical compositions containing polyoxoanions, methods of using them alone or in combination with other compounds, such as AZT and Poly-I:C for the treatment of retroviruses. Also disclosed are novel polyoxoanions.

REFERENCES:
Domaille, J. Am. Chem. Soc., 1984, 106, 7677-7687, "1-and 2-Dimensional Tungsten-183 and Vanadium-51 NMR Characterization of Isopolymetalates and Heteropolymetalates".
Domaille et al, J. Am. Chem. Soc., 1986, 108, 2108-2109, "Synthesis and Structural Characterization of the First Phosphorous-Centered Baker-Figgis-.gamma.-Dodecametalate: .gamma.Cs.sub.5 [PV.sub.2 W.sub.10 O.sub.40 ].multidot..times.H.sub.2 O".
Altenars et al, Inorganic Chemistry, vol. 14, No. 2, 1975, pp. 417-421, "Models for Heteropoly Blues, Degrees of Valence Trapping in Vanadium (IV)-and Molybdenum(V)-Substituted Keggin Anions".

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