Inhibition of H. pylori proliferation

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

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514 11, 530311, 530317, 530328, A61K 3743, C07K 726

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active

059689030

ABSTRACT:
The present invention is directed to a method of using somatostatin or a somatostatin agonist to inhibit the proliferation of Helicobacter pylori (H. pylori), which comprises administering to a patient in need thereof an effective amount of said somatostatin or somatostatin agonist. Preferably, a somatostatin sub-type receptor 2 (SSTR-2) selective somatostatin agonist is administered in a method of this invention. The inhibition of H. pylori proliferation is useful in treating various gastroduodenal diseases such as peptic ulcers, gastric cancer and gastric lymphoma.

REFERENCES:
patent: 4133782 (1979-01-01), Vale, Jr. et al.
patent: 4146612 (1979-03-01), Veber
patent: 4190575 (1980-02-01), Sarantakis
patent: 4190648 (1980-02-01), Veber
patent: 4209426 (1980-06-01), Sarantakis
patent: 4211693 (1980-07-01), Rivier et al.
patent: 4215039 (1980-07-01), Sarantakis
patent: 4224190 (1980-09-01), Villadsen et al.
patent: 4224199 (1980-09-01), Meyers et al.
patent: 4235886 (1980-11-01), Freidinger et al.
patent: 4238481 (1980-12-01), Rink et al.
patent: 4261885 (1981-04-01), Sakakibara et al.
patent: 4282143 (1981-08-01), Sarantakis
patent: 4291022 (1981-09-01), Sandrin et al.
patent: 4310518 (1982-01-01), Freidinger et al.
patent: 4316890 (1982-02-01), Kamber et al.
patent: 4328214 (1982-05-01), Rink et al.
patent: 4358439 (1982-11-01), Sieber et al.
patent: 4360516 (1982-11-01), Freidinger et al.
patent: 4369179 (1983-01-01), Rink et al.
patent: 4395403 (1983-07-01), Bauer et al.
patent: 4435385 (1984-03-01), Bauer et al.
patent: 4485101 (1984-11-01), Coy et al.
patent: 4486415 (1984-12-01), Freidinger
patent: 4522813 (1985-06-01), Nutt
patent: 4585755 (1986-04-01), Morgan et al.
patent: 4603120 (1986-07-01), Kamber
patent: 4650787 (1987-03-01), Schally et al.
patent: 4684620 (1987-08-01), Hruby et al.
patent: 4725577 (1988-02-01), Schally et al.
patent: 4728638 (1988-03-01), Bauer et al.
patent: 4853371 (1989-08-01), Coy et al.
patent: 4871717 (1989-10-01), Coy et al.
patent: 4904642 (1990-02-01), Coy et al.
patent: 5552520 (1996-09-01), Kim et al.
Warren, J.R., et al., The Lancet, Jun. 4, 1983, pp. 1273-1275.
Marshall, B.J., et al., The Lancet, Jun. 16, 1984, pp. 1311-1314.
Rao, R.K., Life Sciences, vol. 48, No. 18, pp. 1685-1704 (1991).
Kaneko, H., et al., Digestive Diseases and Sciences, vol. 37, No. 3. (Mar. 1992), pp. 409-416.
Moss, S.F., et al., The Lancet, vol. 340: Oct. 17, 1992, pp. 930-932.
Calam, J., Annals of Medicine, 27: 569-573, 1995.
Chiba, T., et al., Gut Peptides: Biochemistry and Physiology, eds. John H. Walsh and Graham J. Dockray, Raven Press, Ltd. NY, 1994, pp. 123-145.
Lee, J., et al.,Gastroenterology, 1997; 113: S99-S106.
Gotz, J.M., et al., Scand. J. Gastroenterol., 1995; 30: 1064-1068.
Haruma, K., et al., Scand. J. Gastroenterol., 1995; 30: 550-553.
Alfven, G., et al., Acta Paediatr, 82: 967-970, 1993.
Sumii, M., et al., Am. J. Gastroentero., vol. 89, No. 9, 1994 pp. 1515-1519.
Horvath, A., "Conformation of Somatostatin Analogues Having Antitumor Activity", Peptides, 1992, C.H. Schneider and A.N. Eberle (Eds.) pp.533-534.
Van Binst, Georges and Dirk Tourwe, "Backbone Modifications in Somatostatin Analogues: Relation Between Conformation and Activity", Peptide Research, pp. 8-13.

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