Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1995-04-21
1998-06-16
Owens, Amelia Averill
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514460, 514471, 514473, 549273, 549293, 549294, 549321, A61K 3135
Patent
active
057671478
ABSTRACT:
This invention relates to novel haloenol lactone compounds. These compounds have the following general structure: ##STR1## in which Ar is an aryl group and Y is a haloenol lactone moiety. The compounds of the invention are useful for the specific measurement of particular isoenzymes of glutathione S-transferase. Measurement of glutathione S-transferase isoenzymes has importance in diagnostic medicine. The compounds of the invention are also useful for treatment of drug resistance in cancer and for preventing herbicide resistance in plants.
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Hammock Bruce D.
Jones A. Daniel
Mitchell Alyson E.
Zheng Jiang
Owens Amelia Averill
The Regents of the University of California
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