Inhibition of exoprotein using amide compositions in absorbent a

Surgery – Means and methods for collecting body fluids or waste material – Absorbent pad for external or internal application and...

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604358, 604367, 604904, 602 48, 424430, 424431, A61F 1315, A61F 1320

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056858728

ABSTRACT:
Absorbent articles, such as catamenial tampons, for absorbing body fluids are disclosed which include an effective amount of a nitrogen containing compound to substantially inhibit the production of exotoxins by Gram positive bacteria. The compound is one or more nitrogen containing compounds having the general formula ##STR1## wherein R.sub.1, inclusive of the carbonyl carbon, is an alkyl group having 8 to 18 carbon atoms and R.sub.2 and R.sub.3 can be the same or different. Moieties R.sub.2 and R.sub.3 can be selected from hydrogen and an alkyl group having 1 to about 12 carbon atoms which may contain one or more substituent groups selected from ester, ether, amine, hydroxyl, carboxyl, carboxyl salts, sulfonate, sulfonate salts and mixtures thereof. The compound is effective in substantially inhibiting the production of TSST-1 and Enterotoxin-B from S. aureus bacteria.

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