Inhibition of enveloped viruses with phenyl ketones

Details Inhibition of enveloped viruses with phenyl ketones Inhibition of enveloped viruses with phenyl ketones

1977-10-03

1982-06-08

Goldberg, Jerome D.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

42424857, 42424858, 424330, H61K 2700, A61K 31445, A61K 31135

Patent

active

043339417

ABSTRACT:
Enveloped viruses such as rhabdoviruses, herpes viruses, influenza viruses, .alpha. viruses and paramyxo viruses are inactivated by contacting the viruses or virus infected cells with a .beta.-aminophenylketone compound such as 4-n-butoxy-.beta.-(1-piperidyl)propiophenone hydrochloride; 3,4-dichloro-.beta.-(1-piperidyl)propiophenone; 4-n-decyloxy-.beta.-(1-piperidyl)propiophenone; or 4-n-butoxy-.beta.-(N,N-diethylamino)propiophenone.

REFERENCES:
Ship et al., Oral Surgery, Oral Medicine and Oral Pathology, vol. 13, No. 5, 1960, pp. 630-631.
Catalog, Dow Pharmaceuticals, The Dow Chemical Co., Aug. 1972.

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