Inhibition of CYP450 1A2, 2A6, 2C9, 2C19, 2D6, 2E1, and 3A4...

Details Inhibition of CYP450 1A2, 2A6, 2C9, 2C19, 2D6, 2E1, and 3A4... Inhibition of CYP450 1A2, 2A6, 2C9, 2C19, 2D6, 2E1, and 3A4...

2006-08-29

2006-08-29

Leith, Patricia (Department: 1655)

Drug, bio-affecting and body treating compositions

Plant material or plant extract of undetermined constitution...

Reexamination Certificate

active

07097865

ABSTRACT:
A method of inhibiting chytochrome P450 enzymes selected from the group consisting of CYP1A2, CYP2A6 and CYP3A4 comprises the step of administering an effective inhibition amount of AHT-323A botanical extract to a patient.

REFERENCES:
patent: 4005108 (1977-01-01), Kupchan et al.
patent: 5192817 (1993-03-01), Takaishi et al.
patent: 5430054 (1995-07-01), Qian et al.
Li et al., Cyopreserved human hepatocytes: characterization of drug-metabolizing enzyme activities and applications in higher throughput screening assays for hepatotoxicity, metabolic stability, and drug-drug interaction potential,Chem. Biol. Interact. 121, 17-35 (1999).
Li et al., Isolation and culturing of hepatocytes from human livers.,J. Tiss. Culture Methods14, 139-146 (1992).
Loretz et al., Optimization of cryopreservation procedures for rat and human hepatocytes.,Xenobiotica19(5), 489-498.
Ruegg et al, Cytochrome-P450 induction and conjugated metabolism in primary human hepatocytes after cryopreservation,In Vitro Toxicol. 10(2), 217-222 (1997).

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