Inhibition of cell adhesion for reducing cancer cell metastases

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...

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4241951, A61K 3120, A61K 3578

Patent

active

051419580

ABSTRACT:
Lipids obtained from blackcurrant seed are used for preventing proliferation and dissemination of cancerous metastases in patients.

REFERENCES:
patent: 4526793 (1985-07-01), Ingenbleed et al.
patent: 4888326 (1989-12-01), Horrobin
Horrobin, David F., "The Reversibility of Cancer: The Relevance of Cyclic AMP, Calcium, Essential Fatty Acids and Prostaglandin El", Medical Hypotheses, vol. 6, pp. 469-486, 1980.
Horrobin, D. F., "Cellular Basis of Prolactin Action: Involvement of Cyclic Nucleotides, Polyamines, Prostaglandins, Steroids, Thyroid Hormones, Na/K ATPases and Calcium: Relevance to Breast Cancer and the Menstrual Cycle", Medical Hypotheses, vol. 5, pp. 599-620, 1979.
Humphries, Martin J., et al., "A Synthetic Peptide from Fibronectin Inhibits Experimental Metastasis of Murine Melanoma Cells", Science, Jul. 1986, pp. 467-470.
Humphries, Martin J., et al., "Investigation of the Biological Effects of Anti-Cell Adhesive Synthetic Peptides that Inhibit Experimental Metastasis of B16-F10 Murine Melanoma Cells", J. Clin. Invest., 81: March, 1988, pp. 782-783, 787-790.
Honn, Kenneth V., et al., "Prostacyclin: A Potent Antimetastatic Agent", Science, 212: Mar, 1981, pp. 1270-1272.

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