Inhibition of bone loss by 4-substituted-5-hydroxy-2(5H)-furanon

Details Inhibition of bone loss by 4-substituted-5-hydroxy-2(5H)-furanon Inhibition of bone loss by 4-substituted-5-hydroxy-2(5H)-furanon

1988-06-06

1990-04-10

Raymond, Richard L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

540103, 549320, 549435, C07D30732

Patent

active

049162411

ABSTRACT:
This invention relates to 4-substituted-5-hydroxy-2(5H)-furanones, to the process for their preparation, to pharmaceutical compositions containing said 4-substituted-5-hydroxy-2(5H)-furanones and to the use of said 4-substituted-5-hydroxy-2(5H)-furanones for modifying the balance between bone production and bone resorption in a host animal, including man.

REFERENCES:
patent: 3436390 (1969-04-01), Lefebvre et al.
patent: 4447445 (1984-05-01), Jacobs et al.
Bourguignon et al., "Journal of Medicinal Chemistry", vol. 31, No. 5, pp. 893-897, May 1988.

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